Prednisone tablets are a powerful medication that can be used to treat a wide range of conditions, from autoimmune diseases to severe allergies. These tablets are a type of corticosteroid, a class of drugs that mimic the natural hormones produced by your adrenal glands. While they can be incredibly effective in managing symptoms and reducing inflammation, it’s crucial to understand their mechanism of action, potential side effects, and proper usage to ensure safe and successful treatment.
Prednisone tablets work by suppressing the immune system and reducing inflammation. They bind to specific receptors within cells, triggering a cascade of events that ultimately lead to the production of anti-inflammatory proteins. This mechanism makes them particularly useful in treating conditions characterized by excessive immune activity, such as rheumatoid arthritis, lupus, and inflammatory bowel disease.
Prednisone Tablets
Prednisone tablets are a type of medication known as a corticosteroid. Corticosteroids are powerful medications that work by reducing inflammation in the body. They are commonly used to treat a wide range of conditions, from autoimmune diseases to allergic reactions.
Medical Classification of Prednisone Tablets
Prednisone tablets belong to a class of medications called corticosteroids. Corticosteroids are synthetic hormones that mimic the effects of cortisol, a naturally occurring hormone produced by the adrenal glands. Prednisone is classified as a glucocorticoid, a type of corticosteroid that has a strong anti-inflammatory effect.
Uses and Applications of Prednisone Tablets
Prednisone tablets are used to treat a wide variety of conditions, including:
- Autoimmune diseases: Prednisone is often used to treat autoimmune diseases such as rheumatoid arthritis, lupus, and inflammatory bowel disease. It works by suppressing the immune system, reducing inflammation and pain.
- Allergic reactions: Prednisone can be used to treat severe allergic reactions, such as anaphylaxis. It can help reduce inflammation and prevent further allergic reactions.
- Asthma: Prednisone can be used to treat severe asthma attacks. It helps to open up the airways and reduce inflammation in the lungs.
- Skin conditions: Prednisone can be used to treat a variety of skin conditions, including eczema, psoriasis, and dermatitis. It can help reduce inflammation and itching.
- Cancer: Prednisone is sometimes used to treat certain types of cancer, such as leukemia and lymphoma. It can help to reduce tumor size and control the spread of cancer cells.
- Organ transplantation: Prednisone is used to prevent organ rejection after transplantation. It suppresses the immune system, reducing the risk of the body attacking the transplanted organ.
Common Conditions Treated with Prednisone Tablets
Prednisone is used to treat a wide range of conditions, some of the most common include:
- Rheumatoid arthritis: Prednisone is often used to treat rheumatoid arthritis, a chronic inflammatory disease that affects the joints. It can help to reduce inflammation, pain, and stiffness.
- Lupus: Prednisone is also used to treat lupus, an autoimmune disease that can affect many parts of the body, including the skin, joints, kidneys, and heart. It can help to reduce inflammation and control the symptoms of lupus.
- Inflammatory bowel disease: Prednisone is commonly used to treat inflammatory bowel disease (IBD), a group of conditions that cause inflammation in the digestive tract. It can help to reduce inflammation, pain, and diarrhea.
- Asthma: Prednisone is used to treat severe asthma attacks. It helps to open up the airways and reduce inflammation in the lungs.
- Eczema: Prednisone can be used to treat eczema, a skin condition that causes dry, itchy, and inflamed skin. It can help to reduce inflammation and itching.
- Psoriasis: Prednisone is also used to treat psoriasis, a skin condition that causes red, scaly patches on the skin. It can help to reduce inflammation and clear up the skin.
Mechanism of Action: Prednisone Tablets
Prednisone tablets exert their therapeutic effects by mimicking the actions of naturally occurring glucocorticoid hormones within the body. This mechanism involves a complex interplay of molecular interactions, affecting various cellular processes and ultimately leading to the desired clinical outcomes.
Glucocorticoid Receptor Binding, Prednisone tablets
Prednisone, upon entering the body, is metabolized to its active form, prednisolone. Prednisolone then binds to glucocorticoid receptors (GRs), which are present in the cytoplasm of target cells. The binding of prednisolone to GRs triggers a conformational change in the receptor, leading to the formation of a complex that translocates into the nucleus.
Gene Transcription Modulation
Once inside the nucleus, the prednisolone-GR complex interacts with specific DNA sequences called glucocorticoid response elements (GREs) located in the promoter regions of target genes. This interaction modulates gene transcription, either enhancing or suppressing the expression of various proteins involved in inflammatory and immune responses.
Anti-inflammatory and Immunosuppressive Effects
The modulation of gene transcription by prednisolone-GR complex leads to a cascade of downstream effects, resulting in the anti-inflammatory and immunosuppressive actions of prednisone.
Specific Targets and Pathways
Prednisone’s effects are mediated through its interaction with a wide range of targets and pathways, including:
- Inhibition of inflammatory mediators: Prednisone suppresses the production of pro-inflammatory cytokines such as TNF-α, IL-1, and IL-6, which are key players in the inflammatory cascade.
- Induction of anti-inflammatory proteins: Prednisone stimulates the production of anti-inflammatory proteins, such as annexin-1, which help to dampen the inflammatory response.
- Suppression of immune cell activation: Prednisone inhibits the activation and proliferation of immune cells, such as T lymphocytes and B lymphocytes, reducing their ability to mount an immune response.
- Modulation of vascular permeability: Prednisone reduces vascular permeability, minimizing fluid leakage and tissue edema associated with inflammation.
Dosage and Administration
Prednisone is typically administered orally, usually in tablet form. The specific dosage and duration of treatment vary depending on the condition being treated, the patient’s age, weight, and overall health. It’s crucial to follow your doctor’s instructions carefully and not adjust the dosage without consulting them.
Standard Prednisone Tablet Dosages
Prednisone dosages are typically measured in milligrams (mg). The standard dosage range varies depending on the specific condition being treated. Here are some examples of common dosage ranges for various conditions:
- Asthma: 5-60 mg daily
- Rheumatoid arthritis: 5-60 mg daily
- Lupus: 5-60 mg daily
- Crohn’s disease: 20-60 mg daily
- Ulcerative colitis: 20-60 mg daily
- Allergic reactions: 10-60 mg daily
- Skin conditions: 5-60 mg daily
Frequency and Duration of Treatment Regimens
Prednisone is usually taken once or twice daily, with or without food. The duration of treatment depends on the specific condition and the patient’s response to therapy.
- Short-term treatment: For conditions like allergic reactions, prednisone may be prescribed for a few days or weeks.
- Long-term treatment: For chronic conditions like rheumatoid arthritis or lupus, prednisone may be taken for months or even years, often in conjunction with other medications.
Factors Influencing Dosage Adjustments
Several factors can influence the dosage of prednisone, including:
- Patient age: Children and elderly individuals may require lower dosages than adults.
- Patient weight: Higher doses may be needed for heavier individuals.
- Condition severity: More severe conditions may require higher dosages.
- Response to treatment: If the condition is not improving with the current dosage, the doctor may increase it.
- Side effects: If the patient experiences significant side effects, the doctor may lower the dosage.
Potential Side Effects
Prednisone, like most medications, can cause side effects. These can range from mild and temporary to serious and long-lasting. Understanding the potential side effects of prednisone is crucial for making informed decisions about your treatment.
Common Side Effects
Prednisone can cause a variety of side effects, some of which are more common than others. These side effects can vary depending on the dose and duration of treatment.
- Gastrointestinal: Prednisone can irritate the stomach lining, leading to heartburn, indigestion, ulcers, and even bleeding.
- Mood Changes: Prednisone can affect mood, leading to irritability, anxiety, depression, and insomnia.
- Weight Gain: Prednisone can cause fluid retention and an increase in appetite, leading to weight gain.
- Skin Changes: Prednisone can cause acne, thinning of the skin, and increased susceptibility to bruising.
- Muscle Weakness: Prednisone can weaken muscles, making it difficult to perform daily activities.
- Increased Blood Sugar: Prednisone can raise blood sugar levels, which can be problematic for people with diabetes.
- Cataracts and Glaucoma: Long-term prednisone use can increase the risk of developing cataracts and glaucoma.
Potential Risks and Complications of Long-Term Use
Long-term prednisone use can lead to more serious side effects and complications. These include:
- Osteoporosis: Prednisone can weaken bones, increasing the risk of fractures.
- Cushing’s Syndrome: Long-term prednisone use can mimic the effects of Cushing’s syndrome, a hormonal disorder characterized by weight gain, high blood pressure, and other symptoms.
- Immune Suppression: Prednisone weakens the immune system, making you more susceptible to infections.
- Withdrawal Syndrome: Abruptly stopping prednisone after long-term use can lead to withdrawal symptoms, including fatigue, muscle weakness, and joint pain.
Managing and Mitigating Potential Side Effects
While side effects are a possibility, there are ways to manage and mitigate them.
- Follow your doctor’s instructions: Taking prednisone as prescribed is crucial for minimizing side effects.
- Take prednisone with food: Taking prednisone with food can help reduce stomach irritation.
- Avoid alcohol: Alcohol can worsen prednisone’s side effects.
- Stay active: Regular exercise can help manage weight gain and improve muscle strength.
- Monitor your blood sugar: If you have diabetes, it’s essential to monitor your blood sugar levels closely.
- Report any side effects to your doctor: It’s important to communicate any side effects you experience to your doctor so they can adjust your treatment plan if necessary.
Interactions and Precautions
Prednisone can interact with various medications and substances, potentially affecting its efficacy or increasing the risk of side effects. It is crucial to inform your doctor about all medications, supplements, and herbal remedies you are taking, as well as any allergies or medical conditions you have.
Drug Interactions
Prednisone can interact with several medications, including:
- Blood thinners (anticoagulants): Prednisone can increase the risk of bleeding when taken with blood thinners like warfarin or heparin.
- Digoxin: Prednisone can increase the levels of digoxin in the blood, potentially leading to toxicity.
- Antibiotics: Prednisone can interact with certain antibiotics, such as rifampin and erythromycin.
- Anti-fungal medications: Prednisone can interact with certain anti-fungal medications, such as ketoconazole and itraconazole.
- Anti-seizure medications: Prednisone can interact with certain anti-seizure medications, such as phenytoin and carbamazepine.
- Diabetes medications: Prednisone can increase blood sugar levels and may require adjustments to diabetes medications.
Substances to Avoid
While on prednisone, it is important to avoid certain substances, including:
- Alcohol: Alcohol can increase the risk of stomach ulcers and other side effects associated with prednisone.
- Caffeine: Caffeine can worsen insomnia, a potential side effect of prednisone.
- Grapefruit juice: Grapefruit juice can interact with prednisone and increase its levels in the blood.
Precautions for Underlying Health Conditions
Individuals with certain health conditions should take special precautions when using prednisone:
- Diabetes: Prednisone can increase blood sugar levels, requiring careful monitoring and adjustments to diabetes medications.
- High blood pressure: Prednisone can raise blood pressure, requiring careful monitoring and adjustments to medications.
- Osteoporosis: Prednisone can weaken bones and increase the risk of fractures.
- Glaucoma: Prednisone can increase eye pressure and worsen glaucoma.
- Mental health conditions: Prednisone can worsen mood swings, anxiety, and depression.
- Infections: Prednisone can suppress the immune system, making you more susceptible to infections.
- Liver disease: Prednisone can be metabolized by the liver, and individuals with liver disease may require dose adjustments.
- Kidney disease: Prednisone can be excreted by the kidneys, and individuals with kidney disease may require dose adjustments.
Prednisone and Pregnancy
Prednisone is a corticosteroid medication that is commonly used to treat a variety of conditions, including inflammation, autoimmune disorders, and allergies. While prednisone is generally safe and effective, it’s important to understand its potential effects during pregnancy. This section will discuss the safety of prednisone during pregnancy, explore the potential risks and benefits for both mother and fetus, and provide recommendations for managing prednisone use during pregnancy.
Potential Risks and Benefits
Prednisone use during pregnancy can be associated with both potential risks and benefits. The decision to use prednisone during pregnancy should be made on a case-by-case basis, carefully weighing the potential risks and benefits for both the mother and the fetus.
Risks for the Mother
- Increased risk of infections: Prednisone can suppress the immune system, making the mother more susceptible to infections. This is particularly important during pregnancy, as the mother’s immune system is already compromised.
- High blood pressure: Prednisone can increase blood pressure, which can be a concern during pregnancy.
- Gestational diabetes: Prednisone can increase the risk of developing gestational diabetes, a condition that affects blood sugar levels during pregnancy.
- Premature birth: Prednisone use has been linked to an increased risk of premature birth, especially in the third trimester.
- Other side effects: Prednisone can also cause other side effects during pregnancy, such as weight gain, mood changes, and insomnia.
Risks for the Fetus
- Cleft palate: Prednisone use during pregnancy has been linked to an increased risk of cleft palate in the fetus.
- Low birth weight: Prednisone use has been associated with low birth weight in infants.
- Premature birth: As mentioned above, prednisone can also increase the risk of premature birth for the fetus.
- Other developmental problems: In some cases, prednisone use during pregnancy has been linked to other developmental problems in the fetus.
Benefits for the Mother
- Treatment of severe conditions: Prednisone can be essential for treating severe conditions in the mother, such as lupus, rheumatoid arthritis, or severe asthma. In these cases, the benefits of treating the mother’s condition may outweigh the potential risks to the fetus.
- Prevention of complications: Prednisone can also be used to prevent complications during pregnancy, such as preterm labor or preeclampsia.
Benefits for the Fetus
- Improved fetal health: In some cases, prednisone may be used to improve fetal health, such as in cases of fetal distress or lung immaturity.
Managing Prednisone Use During Pregnancy
If you are pregnant and need to take prednisone, it is important to discuss the risks and benefits with your doctor. They will help you weigh the potential risks and benefits of prednisone use during pregnancy and make the best decision for you and your baby.
- Use the lowest possible dose: Your doctor will try to prescribe the lowest possible dose of prednisone to minimize the potential risks to you and your baby.
- Take prednisone as directed: It is important to take prednisone exactly as prescribed by your doctor. Do not stop taking prednisone without talking to your doctor.
- Monitor your blood sugar levels: If you have diabetes or are at risk for gestational diabetes, your doctor will monitor your blood sugar levels closely while you are taking prednisone.
- Monitor your blood pressure: Your doctor will also monitor your blood pressure closely while you are taking prednisone.
- Report any side effects: It is important to report any side effects you experience while taking prednisone to your doctor.
Prednisone and Breastfeeding
Prednisone is a corticosteroid medication that can be used to treat a variety of conditions, including inflammation, autoimmune disorders, and allergies. While prednisone is generally safe and effective, it is important to consider the potential impact on breastfeeding infants before starting treatment.
Prednisone can be transferred to breast milk and may have some effects on the infant. It is essential to weigh the potential risks and benefits of continuing breastfeeding while taking prednisone.
Potential Impact on Breastfeeding Infants
Prednisone can potentially impact breastfeeding infants in various ways. It is important to be aware of these potential effects and discuss them with your healthcare provider.
- Decreased milk production: Prednisone can potentially decrease milk production in some mothers. However, this is not a common side effect, and many women are able to continue breastfeeding successfully while taking prednisone.
- Possible side effects in infants: Prednisone can pass into breast milk and may cause potential side effects in infants, such as:
- Growth suppression
- Weight gain
- Increased risk of infections
- Changes in blood sugar levels
These side effects are rare and usually occur only with prolonged exposure to high doses of prednisone.
- Suppressed immune system: Prednisone can suppress the infant’s immune system, making them more susceptible to infections. However, this risk is generally low, especially with short-term use of prednisone.
Risks and Benefits of Continuing Breastfeeding
The decision to continue breastfeeding while taking prednisone should be made on a case-by-case basis, considering the potential risks and benefits for both the mother and the infant.
- Benefits of breastfeeding: Breastfeeding provides numerous benefits for both the mother and the infant, including:
- Provides essential nutrients and antibodies
- Reduces the risk of infections and allergies
- Promotes bonding and emotional well-being
- May help with weight management and postpartum recovery
- Risks of breastfeeding while on prednisone: While breastfeeding is generally safe while taking prednisone, there are potential risks to consider, such as:
- Potential side effects in the infant
- Suppressed immune system in the infant
Managing Prednisone Use During Breastfeeding
Here are some tips for managing prednisone use during breastfeeding:
- Discuss with your healthcare provider: It is essential to discuss your breastfeeding plans with your healthcare provider before starting prednisone. They can assess your individual situation and advise you on the best course of action.
- Monitor your infant: Observe your infant for any potential side effects of prednisone. If you notice any unusual symptoms, contact your healthcare provider immediately.
- Consider alternative medications: In some cases, your healthcare provider may recommend an alternative medication that is safer for breastfeeding.
- Pump and discard milk: If your healthcare provider advises you to avoid breastfeeding while taking prednisone, you can pump and discard your milk for a short period. This helps to maintain milk production.
Withdrawal and Tapering
Prednisone, like other corticosteroids, should not be stopped abruptly. Stopping abruptly can lead to serious withdrawal symptoms. Therefore, your doctor will gradually reduce your prednisone dosage over time, a process called tapering.
Tapering prednisone is essential to minimize the risk of withdrawal symptoms. This gradual reduction allows your body to adjust to producing its own cortisol again, preventing sudden hormonal fluctuations that can cause adverse effects.
Managing Withdrawal Symptoms
- Fatigue and Weakness: These are common withdrawal symptoms. Ensure you get enough rest, eat a balanced diet, and avoid strenuous activities until your energy levels improve.
- Joint Pain and Stiffness: Prednisone withdrawal can exacerbate existing joint pain. Consult your doctor about pain management strategies, such as over-the-counter pain relievers or physical therapy.
- Mood Changes: Prednisone withdrawal can cause mood swings, irritability, and even depression. It’s important to be aware of these potential changes and seek support from loved ones or a mental health professional if needed.
Patient Education and Information
This information sheet provides essential details about prednisone tablets, including how it works, potential side effects, and important precautions. It is crucial to understand this information to use prednisone safely and effectively.
Dosage and Administration
Prednisone is a medication prescribed by your doctor to treat various conditions. It is crucial to follow your doctor’s instructions regarding dosage and frequency of administration. The dosage and duration of treatment depend on your specific condition and response to the medication. Prednisone tablets are usually taken by mouth with a glass of water.
Side Effects
Like all medications, prednisone can cause side effects. Some common side effects include:
- Weight gain
- Mood swings
- Increased appetite
- Insomnia
- High blood sugar
- Increased risk of infections
If you experience any severe or persistent side effects, contact your doctor immediately.
Interactions
Prednisone can interact with other medications, including over-the-counter drugs and herbal supplements. It is essential to inform your doctor about all medications you are taking, including prescription and non-prescription drugs, vitamins, and herbal supplements.
Precautions
Prednisone can affect your immune system, making you more susceptible to infections. It is crucial to avoid contact with people who are sick and practice good hygiene, such as frequent hand washing.
Important Considerations
- Prednisone should not be abruptly stopped. Your doctor will gradually reduce your dosage to prevent withdrawal symptoms.
- Prednisone can affect blood sugar levels, especially in people with diabetes. It is essential to monitor your blood sugar regularly if you have diabetes.
- Prednisone can cause bone thinning. It is essential to maintain a healthy diet and engage in regular exercise to maintain bone health.
- Prednisone can cause mood swings and emotional instability. It is essential to be aware of these potential effects and seek help if you experience significant mood changes.
- Prednisone can interact with certain foods and drinks, such as grapefruit juice. It is essential to discuss these interactions with your doctor.
Adherence to Prescribed Regimen
It is crucial to adhere to your doctor’s instructions regarding dosage, frequency of administration, and duration of treatment. Taking prednisone as prescribed is essential for its effectiveness and safety.
Prednisone Alternatives
Prednisone is a powerful corticosteroid medication used to treat a wide range of conditions, including inflammatory diseases, autoimmune disorders, and certain types of cancer. While prednisone can be highly effective, it can also cause significant side effects, particularly with long-term use. This has led to the development of alternative medications and treatment options for conditions treated with prednisone.
Alternative Medications
Prednisone alternatives offer various benefits, including reduced side effect profiles, improved patient compliance, and tailored treatment approaches. These alternatives can be broadly categorized into different classes of medications, each with its own mechanism of action and unique advantages.
- Nonsteroidal Anti-inflammatory Drugs (NSAIDs): NSAIDs, such as ibuprofen and naproxen, are commonly used to manage pain and inflammation. They work by inhibiting the production of prostaglandins, chemicals that contribute to inflammation. While NSAIDs are generally well-tolerated, they can cause gastrointestinal side effects, including ulcers and bleeding, particularly with long-term use.
- Disease-Modifying Anti-rheumatic Drugs (DMARDs): DMARDs, such as methotrexate and sulfasalazine, are used to treat autoimmune diseases like rheumatoid arthritis. They work by suppressing the immune system, reducing inflammation and joint damage. DMARDs can take several weeks or months to become effective and can cause side effects, including liver damage and infections.
- Biologic Therapies: Biologics are a newer class of medications that target specific proteins involved in the inflammatory process. Examples include etanercept, infliximab, and adalimumab. Biologics are highly effective in treating autoimmune diseases but can be expensive and may increase the risk of infections.
- Immunosuppressants: Immunosuppressants, such as azathioprine and cyclosporine, are used to suppress the immune system, particularly in organ transplantation. They can also be used to treat autoimmune diseases, but they carry a significant risk of infections and other side effects.
Choosing the Most Appropriate Treatment Option
Selecting the most appropriate treatment option depends on several factors, including the specific condition being treated, the severity of the symptoms, the patient’s medical history, and their individual risk factors.
- Condition: The type of condition being treated will determine the most appropriate medication or treatment approach. For example, NSAIDs are often effective for mild to moderate pain and inflammation, while DMARDs or biologics may be needed for more severe autoimmune diseases.
- Severity: The severity of the symptoms will also influence treatment choices. For severe conditions, more potent medications, such as biologics or immunosuppressants, may be required.
- Medical History: The patient’s medical history, including any allergies or pre-existing conditions, should be considered. For example, patients with a history of gastrointestinal problems may not be suitable for NSAIDs.
- Risk Factors: Individual risk factors, such as age, smoking status, and family history, can also play a role in treatment decisions. For example, older adults may be more susceptible to side effects from certain medications.
Comparison of Effectiveness and Side Effects
The effectiveness and side effect profiles of different treatment options vary widely.
- Prednisone: Prednisone is highly effective in reducing inflammation and suppressing the immune system. However, it can cause significant side effects, including weight gain, mood swings, high blood pressure, and osteoporosis. Long-term use can also lead to Cushing’s syndrome, a condition characterized by weight gain, muscle weakness, and high blood sugar levels.
- NSAIDs: NSAIDs are generally well-tolerated, but they can cause gastrointestinal side effects, such as ulcers and bleeding, particularly with long-term use. They can also increase the risk of heart attack and stroke in some individuals.
- DMARDs: DMARDs can be effective in treating autoimmune diseases, but they can take several weeks or months to become effective and can cause side effects, including liver damage and infections.
- Biologics: Biologics are highly effective in treating autoimmune diseases but can be expensive and may increase the risk of infections.
- Immunosuppressants: Immunosuppressants can be effective in suppressing the immune system but carry a significant risk of infections and other side effects.
Research and Future Directions
Prednisone, a widely used corticosteroid, has been a cornerstone of treatment for various inflammatory and autoimmune conditions for decades. Ongoing research continues to unravel its complex mechanisms of action, identify novel therapeutic applications, and explore strategies to mitigate potential side effects.
Emerging Trends and Developments in Corticosteroid Therapy
The field of corticosteroid therapy is constantly evolving, with researchers exploring new avenues to enhance efficacy and minimize adverse effects. Here are some notable trends:
- Targeted Delivery Systems: Researchers are developing targeted delivery systems to deliver corticosteroids directly to the site of inflammation, potentially reducing systemic exposure and minimizing side effects. For example, inhaled corticosteroids are now widely used in the management of asthma, delivering the medication directly to the airways.
- Novel Corticosteroid Analogs: Efforts are underway to synthesize novel corticosteroid analogs with improved potency, selectivity, and reduced side effect profiles. This involves optimizing the chemical structure of corticosteroids to enhance their therapeutic efficacy while minimizing unwanted effects.
- Combination Therapies: Combining corticosteroids with other medications, such as biologics or immunosuppressants, is being investigated to enhance treatment efficacy and potentially reduce the required dose of corticosteroids. This approach may be particularly beneficial for patients with severe or refractory conditions.
Understanding prednisone tablets, from their mechanism of action to potential side effects and interactions, is essential for anyone taking this medication. While they can be a powerful tool in managing various conditions, it’s crucial to use them under the guidance of a healthcare professional. By following your doctor’s instructions, being aware of potential risks, and communicating any concerns, you can optimize your treatment and ensure the best possible outcome.
Prednisone tablets are a common corticosteroid used to treat various conditions, including inflammation and autoimmune disorders. While prednisone works by suppressing the immune system, other medications like palbociclib target specific pathways involved in cell growth and division, often used in cancer treatment. Prednisone’s effects on the immune system can sometimes lead to side effects, making it crucial to discuss potential risks and benefits with a healthcare professional.